Glycine: Key to helping Leaky Gut


Last Updated: March 31, 2017

Important facts about Glycine:

  • Glycine is the 2nd most abundant amino acid of the 20 found in your body making it important in many roles. (1)
  • Glycine is a non-essential amino acid that is important for your brain and your digestive system. It is also required to make parts of your blood.
  • Glycine plays an important role in re building the tissues that line your digestive. Glycine helps form two substances; collagen and gelatin. An abundance of glycine is found in collagen.
  • Glycine helps you tolerate food if you have sensitivities or allergies. Glycine does this by keeping digested food and bacteria in the intestines and colon so that the lining does not develop small openings for small molecules to pass into the bloodstream. When undigested food passes into the blood it creates inflammation. If food continues to pass into the blood continually it is called a Leaky Gut Syndrome.

Symptoms that show you may need Glycine:

  • digestive disorders (food sensitivities, IBS, IBD),
  • fatigue,
  • joint pain
  • anxiety
  • trouble sleeping
  • low immune function

Glycine depletion allows inflammation (2) in your gut. People who suffer from inflammatory bowel diseases or indigestion which include IBS, ulcerative colitis, Crohn’s, leaky gut syndrome and even acid reflux may require testing for glycine.

Glycine is required to make creatine phosphate, nucleic acids, porphyrins and bile. These chemicals help shuttle broken down food to be stored for the creation of energy (ATP). ATP production is crucial to keep you healthy.

Studies are showing that when combined with glutamine and niacin glycine has helped improve chemicals that help with memory loss. (3) Glycine has been shown to improve daytime activity from sleep deprivation for short periods of time. (4).

Glycine has also shown promise in fighting muscle wasting. (5)

Do I need to Supplement with Glycine?

Because glycine is a non-essential amino acid it can be made in small amounts by the body but it is mostly received from our diet. The highest sources of collagen and gelatin are found in animal bones, connective tissue, skin and tendons and ligaments. Many times these parts are thrown away. That means our diets have low levels of glycine in them (approximately 2 grams per day when we should have between 15 and 60 g per day).

Bone broth or soup broth made from slowly boiling animal bones is the easiest way to consume glycine because of the collagen and gelatin content. It is found in meat, poultry, fish, eggs and dairy products. For vegetarians it can be in bananas, kiwi, kale, cauliflower, cabbage, spinach, pumpkin and beans.

The glycine in your diet usually comes in small amounts and because it is a natural amino acid a supplement may be consumed for a higher dose.

Depending on the results of your personal testing, your state of health and your needs, (6) you may consume up to 10 times or more of the normal amount of glycine safely.

It is recommended that you use high quality, food based supplement as not all supplements create the same benefits.

Patients taking metabolic medications, who are ill, experiencing high stress or who are recovering from surgical procedures can use glycine as a tool to recover.

Important to note that glycine is known to have interactions for those taking high doses of medications for mental disorders.

Clinical tests : REAL LIFE STORIES

Recently I tested a young woman who has experienced anxiety issues and digestive problems which has led to increased weight gain and painful joints. After multiple treatments she got tested with our program and found that she was very deficient in glycine. As a doctor this was not the number one thing I was looking for on her tests. It once again showed me the importance of doing the right work to find out what is causing the problems people like her and you for that matter are experiencing. She also received the correct dosage of Glycine to help support the regeneration of her health. It is exciting to see how we now have access to the right tests to find the right solutions for people that need help.

Sources and References

(1): http://aminoacidstudies.org/glycine/
(2): https://www.ncbi.nlm.nih.gov/pubmed/12589194
(3): https://www.ncbi.nlm.nih.gov/pubmed/14609312
(4): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3328957/
(5): https://www.ncbi.nlm.nih.gov/pubmed/23835111
(6): http://www.webmd.com/vitamins-and-supplements/glycine-uses-and-risks#1

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